/* ════════════════════════════════════════════════════════════════
   PLUSEVO CIENCIA · Sistema de diseño científico (light / TSH-style)
   Tipografía: Inter Tight (display+body) · IBM Plex Mono (técnico)
   ════════════════════════════════════════════════════════════════ */
:root{
  --paper:#ffffff;
  --gray-50:#F3F5F8;
  --gray-100:#EAEDF2;
  --gray-150:#E2E6EC;
  --gray-200:#D6DBE3;
  --gray-300:#C2C8D2;

  --ink:#15161B;
  --ink-2:#1E212B;
  --ink-3:#2A2E3C;

  --text:#15161B;
  --text-2:#565C68;
  --text-3:#8A909C;

  --lilac:#7C7AF7;  --lilac-deep:#5B58E0;
  --lilac-2:#B5B4FF; --lilac-1:#D7D6FF; --lilac-0:#EDEDFF;
  --magenta:#C44FE6; --magenta-1:#E8AFFF; --magenta-0:#F7E6FF;
  --blue:#2E92F0; --blue-deep:#1B6FCB; --blue-1:#A9DCFF; --blue-0:#DCEFFF;
  --amber:#F0971C; --amber-deep:#D07A00; --amber-1:#FFCE85; --amber-0:#FFE9CC;
  --rose:#E2557E; --rose-deep:#C23862; --rose-0:#FCE4EC;

  --border:var(--gray-200);
  --border-2:var(--gray-300);

  --fd:'Inter Tight',system-ui,sans-serif;
  --fb:'Inter Tight',system-ui,sans-serif;
  --fm:'IBM Plex Mono',ui-monospace,monospace;

  --maxw:1240px;
  --shard:polygon(18% 0,100% 0,82% 100%,0 100%);
  --bolt:polygon(46% 0,100% 0,60% 42%,92% 42%,30% 100%,52% 54%,8% 54%);
}

*,*::before,*::after{box-sizing:border-box;margin:0;padding:0}
html{scroll-behavior:smooth;font-size:16px;-webkit-text-size-adjust:100%}
body{
  background:var(--paper);color:var(--text);
  font-family:var(--fb);font-weight:400;line-height:1.6;
  overflow-x:hidden;-webkit-font-smoothing:antialiased;text-rendering:optimizeLegibility;
}
::selection{background:var(--lilac);color:#fff}
img{max-width:100%;display:block}
a{color:inherit}

/* ── tipos utilitarios ── */
.mono{font-family:var(--fm)}
.arrow{font-family:var(--fd);font-weight:600;display:inline-block;transform:translateY(-1px)}

/* ════════ NAV ════════ */
nav{position:fixed;top:0;left:0;right:0;z-index:200;
  display:flex;align-items:center;justify-content:space-between;
  padding:16px clamp(20px,4vw,40px);
  background:rgba(255,255,255,.82);backdrop-filter:blur(20px) saturate(1.3);
  border-bottom:1px solid var(--border)}
.brand{display:flex;align-items:center;gap:11px;text-decoration:none;color:var(--ink)}
.brand-mark{width:30px;height:30px;flex:none;background:var(--ink);position:relative;border-radius:3px}
.brand-mark::before{content:'';position:absolute;inset:0;background:var(--lilac);
  clip-path:var(--bolt);transform:scale(.62)}
.brand-name{font-family:var(--fd);font-weight:800;font-size:18px;letter-spacing:-.02em;line-height:1}
.brand-name sup{font-size:9px;font-family:var(--fm);font-weight:500;color:var(--lilac);
  letter-spacing:.04em;vertical-align:super;margin-left:2px}
.brand-logo{height:21px;width:auto;display:block}
.brand-tag{font-family:var(--fm);font-size:11px;font-weight:500;color:var(--lilac-deep);
  letter-spacing:.05em;padding-left:11px;border-left:1px solid var(--border-2);line-height:1}
.fbrand-logo{height:26px;width:auto;display:block}
.bridge-logo{height:34px;width:auto;display:block;margin-bottom:26px;position:relative;z-index:2}
.layer-logo{height:20px;width:auto;display:block;margin-bottom:16px}
.nlinks{display:flex;gap:22px;list-style:none}
.nlinks a{font-family:var(--fm);font-size:11.5px;color:var(--text-2);text-decoration:none;
  letter-spacing:.02em;transition:color .18s;white-space:nowrap}
.nlinks a:hover,.nlinks a.active{color:var(--ink)}
.ncta{display:inline-flex;align-items:center;gap:7px;font-family:var(--fd);font-weight:600;
  font-size:13px;padding:10px 18px;background:var(--ink);color:#fff;text-decoration:none;
  border-radius:4px;transition:background .18s}
.ncta:hover{background:var(--lilac-deep)}
.nav-right{display:flex;align-items:center;gap:24px}

/* ════════ LAYOUT ════════ */
.wrap{max-width:var(--maxw);margin:0 auto;padding:0 clamp(20px,4vw,40px);position:relative}
section{padding:clamp(64px,8vw,120px) 0;position:relative}
.bg-gray{background:var(--gray-50)}
.bg-ink{background:var(--ink);color:#EDEEF2}

/* eyebrow / kicker */
.ey{font-family:var(--fm);font-size:11px;color:var(--lilac-deep);letter-spacing:.08em;
  text-transform:uppercase;margin-bottom:22px;display:flex;align-items:center;gap:9px;font-weight:500}
.ey::before{content:'→';color:var(--lilac);font-family:var(--fd);font-weight:700;transform:none}
.bg-ink .ey{color:var(--lilac-2)}
.bg-ink .ey::before{color:var(--lilac-2)}

/* section title */
.st{font-family:var(--fd);font-weight:800;letter-spacing:-.03em;line-height:1.0;
  font-size:clamp(34px,5.4vw,68px);color:var(--ink);margin-bottom:22px;text-wrap:balance;max-width:18ch}
.st em{font-style:normal;color:var(--lilac)}
.bg-ink .st{color:#fff}
.bg-ink .st em{color:var(--lilac-2)}
.sb{font-size:clamp(15px,1.5vw,18px);color:var(--text-2);line-height:1.65;max-width:64ch;font-weight:400}
.sb strong{color:var(--ink);font-weight:600}
.bg-ink .sb{color:#AfB3BE}
.bg-ink .sb strong{color:#fff}
.label-up{font-family:var(--fm);font-size:10px;color:var(--text-3);letter-spacing:.12em;
  text-transform:uppercase;margin-bottom:8px;font-weight:500}

hr.dv{border:none;border-top:1px solid var(--border);margin:0}

/* ════════ SHARD / BOLT DECOR ════════ */
.shardstack{position:absolute;inset:0;overflow:hidden;pointer-events:none;z-index:0}
.shardstack span{position:absolute;top:-10%;height:130%;width:30%;
  clip-path:var(--shard);opacity:.9;mix-blend-mode:normal}

/* ════════ HERO ════════ */
.hero{position:relative;padding-top:0;background:var(--paper)}
.hero-top{position:relative;overflow:hidden;
  background:linear-gradient(108deg,#FFE3C0 0%,#FFD9E2 24%,#E7DBFF 52%,#D4E6FF 78%,#CFE7FF 100%)}
.hero-top .shardstack span:nth-child(1){left:8%;background:rgba(255,255,255,.34);transform:skewX(0deg)}
.hero-top .shardstack span:nth-child(2){left:30%;background:rgba(255,255,255,.18)}
.hero-top .shardstack span:nth-child(3){left:54%;background:rgba(135,133,255,.16)}
.hero-top .shardstack span:nth-child(4){left:74%;background:rgba(255,255,255,.30)}
.hero-inner{position:relative;z-index:2;max-width:var(--maxw);margin:0 auto;
  padding:clamp(40px,7vw,92px) clamp(20px,4vw,40px) clamp(48px,7vw,96px)}
.hero-overline{font-family:var(--fm);font-size:12px;color:var(--ink);letter-spacing:.04em;
  text-transform:uppercase;margin-bottom:clamp(28px,5vw,56px);display:flex;align-items:center;gap:8px;font-weight:500}
.hero h1{font-family:var(--fd);font-weight:800;letter-spacing:-.035em;line-height:.97;
  font-size:clamp(40px,7.2vw,104px);color:var(--ink);max-width:15ch;text-wrap:balance}
.hero h1 em{font-style:normal;color:var(--lilac-deep)}
.hero-lead{font-size:clamp(16px,1.7vw,20px);color:#3A3E48;line-height:1.55;max-width:60ch;
  margin-top:30px;font-weight:400}
.hero-lead strong{color:var(--ink);font-weight:600}

/* hero chart band */
.hero-data{background:var(--ink);color:#EDEEF2;padding:clamp(40px,6vw,72px) 0}
.hcw-label{font-family:var(--fm);font-size:11px;color:#9CA2AE;letter-spacing:.04em;
  text-transform:uppercase;margin-bottom:26px;display:flex;align-items:center;gap:14px;max-width:70ch}
.hcw-label::after{content:'';flex:1;height:1px;background:rgba(255,255,255,.12)}
.hbars{display:grid;grid-template-columns:repeat(6,1fr);gap:1px;background:rgba(255,255,255,.08);
  border:1px solid rgba(255,255,255,.08);border-radius:6px;overflow:hidden}
.hb-col{background:var(--ink-2);padding:22px 18px 20px;transition:background .18s}
.hb-col:hover{background:var(--ink-3)}
.hb-name{font-family:var(--fd);font-weight:700;font-size:15px;color:#fff;line-height:1.1;margin-bottom:3px;letter-spacing:-.01em}
.hb-ind{font-family:var(--fm);font-size:10px;color:#8A909C;margin-bottom:18px;letter-spacing:.02em}
.hb-bars{display:flex;flex-direction:column;gap:9px;margin-bottom:16px}
.hb-row{display:flex;flex-direction:column;gap:4px}
.hb-meta{display:flex;justify-content:space-between;align-items:baseline}
.hb-nm{font-family:var(--fm);font-size:10px;color:#9CA2AE}
.hb-vl{font-family:var(--fm);font-size:11px;font-weight:500}
.hb-track{height:6px;background:rgba(255,255,255,.08);border-radius:3px;overflow:hidden}
.hb-fill{height:100%;border-radius:3px}
.hb-big{font-family:var(--fd);font-weight:800;font-size:30px;line-height:.9;letter-spacing:-.03em;display:block}
.hb-cap{font-family:var(--fm);font-size:10px;color:#9CA2AE;line-height:1.4;margin-top:6px}
.hb-foot{font-family:var(--fm);font-size:9.5px;color:#6B7280;margin-top:12px;letter-spacing:.02em}
.hero-legend{display:flex;flex-wrap:wrap;gap:22px;align-items:center;padding-top:20px;margin-top:18px;border-top:1px solid rgba(255,255,255,.1)}
.hl-item{display:flex;align-items:center;gap:7px;font-family:var(--fm);font-size:10.5px;color:#AfB3BE}
.hl-dot{width:9px;height:9px;border-radius:2px;flex:none}
.hl-src{margin-left:auto;font-family:var(--fm);font-size:10px;color:#6B7280}

/* credibility strip */
.cred{border-bottom:1px solid var(--border);background:var(--paper)}
.cred-in{display:flex;align-items:center;gap:clamp(20px,5vw,64px);flex-wrap:wrap;padding:26px 0}
.cred-k{font-family:var(--fm);font-size:10.5px;color:var(--text-3);letter-spacing:.1em;text-transform:uppercase}
.cred-logos{display:flex;flex-wrap:wrap;gap:clamp(20px,4vw,46px);align-items:center}
.cred-logos span{font-family:var(--fd);font-weight:700;font-size:clamp(15px,1.6vw,20px);color:#A3A8B2;letter-spacing:-.01em}

/* ════════ SUMMARY ════════ */
.sum-grid{display:grid;grid-template-columns:1.15fr .85fr;gap:clamp(20px,2.5vw,36px);align-items:start;margin-top:18px}
.sum-lead{font-size:clamp(17px,1.8vw,21px);color:var(--text);line-height:1.55;max-width:62ch;font-weight:400}
.sum-lead strong{font-weight:600}
.sum-kpis{display:grid;grid-template-columns:repeat(2,1fr);gap:1px;background:var(--border);
  border:1px solid var(--border);border-radius:8px;overflow:hidden;margin-top:30px}
.kpi{background:var(--paper);padding:26px 24px;min-height:172px}
.kpi-l{font-family:var(--fm);font-size:10px;color:var(--lilac-deep);letter-spacing:.06em;text-transform:uppercase;margin-bottom:14px;font-weight:500}
.kpi-n{font-family:var(--fd);font-weight:800;font-size:46px;color:var(--ink);line-height:.9;letter-spacing:-.03em;margin-bottom:12px}
.kpi-p{font-size:13px;color:var(--text-2);line-height:1.55}
.kpi-p strong{color:var(--ink);font-weight:600}
.sum-list{display:flex;flex-direction:column;gap:1px;background:var(--border);border:1px solid var(--border);border-radius:8px;overflow:hidden}
.sum-item{background:var(--paper);padding:22px 22px}
.sum-item-k{font-family:var(--fm);font-size:10px;color:var(--lilac-deep);letter-spacing:.06em;text-transform:uppercase;margin-bottom:10px;font-weight:500}
.sum-item h3{font-family:var(--fd);font-weight:700;font-size:18px;line-height:1.2;color:var(--ink);margin-bottom:8px;letter-spacing:-.01em}
.sum-item p{font-size:13px;line-height:1.55;color:var(--text-2)}
.sum-item p strong{color:var(--ink);font-weight:600}

/* ════════ IMMERSIVE CHARTS ════════ */
.immersive-head{margin-bottom:clamp(34px,4vw,54px)}
.chart-tabs{display:flex;flex-wrap:wrap;gap:8px;margin-bottom:clamp(28px,3vw,40px)}
.ctab{font-family:var(--fm);font-size:11px;padding:9px 16px;border-radius:999px;
  border:1px solid var(--border-2);background:var(--paper);color:var(--text-2);cursor:pointer;
  letter-spacing:.02em;transition:all .16s;font-weight:500}
.ctab:hover{border-color:var(--ink);color:var(--ink)}
.ctab.on{background:var(--ink);border-color:var(--ink);color:#fff}
.chart-panel{display:none;grid-template-columns:1.25fr .75fr;gap:clamp(20px,2.5vw,40px);align-items:stretch}
.chart-panel.on{display:grid}
.chart-figure-shell{background:var(--gray-50);border:1px solid var(--border);border-radius:14px;
  padding:clamp(24px,3vw,44px);display:flex;align-items:center;justify-content:center;min-height:420px;position:relative;overflow:hidden}
.chart-copy-shell{background:var(--ink);color:#EDEEF2;border-radius:14px;padding:clamp(26px,3vw,40px);display:flex;flex-direction:column}
.chart-kicker{font-family:var(--fm);font-size:10.5px;letter-spacing:.08em;text-transform:uppercase;color:var(--lilac-2);margin-bottom:18px;font-weight:500}
.chart-h{font-family:var(--fd);font-weight:700;font-size:clamp(22px,2.4vw,32px);line-height:1.05;color:#fff;margin-bottom:18px;letter-spacing:-.02em;text-wrap:balance}
.chart-p{font-size:14px;color:#AfB3BE;line-height:1.6;margin-bottom:16px}
.chart-p strong{color:#fff;font-weight:600}
.chart-bullets{display:flex;flex-direction:column;gap:8px;margin:6px 0 4px}
.chart-bullet{padding:13px 15px;border-radius:8px;background:rgba(255,255,255,.05);font-size:12.5px;color:#C5C9D2;line-height:1.5}
.chart-bullet strong{color:#fff;font-weight:600}
.chart-source{margin-top:auto;padding-top:16px;font-family:var(--fm);font-size:10px;color:#7B8290;line-height:1.6;border-top:1px solid rgba(255,255,255,.1)}

/* native charts */
.donut{position:relative;width:min(330px,80%);aspect-ratio:1}
.donut-svg{width:100%;height:100%;display:block}
.donut-hole{position:absolute;inset:25%;background:var(--gray-50);border-radius:50%;
  display:flex;flex-direction:column;align-items:center;justify-content:center;text-align:center}
.donut-n{font-family:var(--fd);font-weight:800;font-size:clamp(40px,7vw,68px);color:var(--ink);line-height:.85;letter-spacing:-.04em}
.donut-l{font-family:var(--fm);font-size:11px;color:var(--text-2);margin-top:8px;max-width:18ch;line-height:1.4}
.donut-key{position:absolute;bottom:-2px;left:0;right:0;display:flex;justify-content:center;gap:18px}

.cbars{width:100%;display:flex;flex-direction:column;gap:18px}
.cbar-row{display:flex;flex-direction:column;gap:7px}
.cbar-top{display:flex;justify-content:space-between;align-items:baseline;font-family:var(--fm);font-size:12px;color:var(--text-2)}
.cbar-top b{font-family:var(--fd);font-weight:700;color:var(--ink);font-size:14px}
.cbar-track{height:30px;background:var(--gray-100);border-radius:5px;overflow:hidden;display:flex}
.cbar-placebo{height:100%;background:var(--lilac);display:flex;align-items:center;padding-left:10px}
.cbar-net{height:100%;background:var(--ink)}
.cbar-tag{font-family:var(--fm);font-size:10px;color:#fff;font-weight:500}

.linechart{width:100%}
.linechart svg{width:100%;height:auto;display:block;overflow:visible}

/* ════════ CRISIS (dark) ════════ */
.crisis-intro{font-family:var(--fd);font-weight:700;font-size:clamp(20px,2.6vw,32px);
  line-height:1.18;max-width:24ch;margin:8px 0 clamp(36px,4vw,54px);letter-spacing:-.02em;color:#fff}
.crisis-intro em{font-style:normal;color:var(--amber-1)}
.case-grid{display:grid;grid-template-columns:repeat(3,1fr);gap:1px;background:rgba(255,255,255,.08);
  border:1px solid rgba(255,255,255,.08);border-radius:8px;overflow:hidden}
.case-card{background:var(--ink-2);padding:26px 26px;transition:background .16s}
.case-card:hover{background:var(--ink-3)}
.stock-badge{display:inline-flex;align-items:center;gap:5px;font-family:var(--fm);font-size:10px;
  padding:4px 9px;border-radius:3px;margin-bottom:14px;letter-spacing:.02em}
.sb-red{background:rgba(226,85,126,.16);color:#FF9CB6}
.case-ticker{font-family:var(--fm);font-size:10px;color:#8A909C;letter-spacing:.06em;text-transform:uppercase;margin-bottom:8px}
.case-company{font-family:var(--fd);font-weight:800;font-size:23px;color:#fff;line-height:1.05;margin-bottom:3px;letter-spacing:-.02em}
.case-drug{font-family:var(--fm);font-size:10.5px;color:var(--lilac-2);margin-bottom:14px;letter-spacing:.01em}
.case-body{font-size:13px;color:#B4B8C2;line-height:1.55;margin-bottom:16px}
.case-body strong{color:#fff;font-weight:600}
.case-delta{display:flex;gap:14px;padding:14px 16px;background:rgba(255,255,255,.04);border-radius:6px;margin-bottom:14px}
.cd-item{flex:1}
.cd-label{font-family:var(--fm);font-size:9px;color:#7B8290;letter-spacing:.06em;text-transform:uppercase;margin-bottom:5px}
.cd-val{font-family:var(--fd);font-weight:800;font-size:21px;color:#fff;letter-spacing:-.02em}
.cd-val.ca{color:var(--lilac-2)}.cd-val.cd{color:#fff}.cd-val.cb{color:var(--amber-1)}
.cd-delta{font-family:var(--fm);font-size:10px;margin-top:3px}
.case-verdict{font-size:11.5px;line-height:1.45;padding:10px 13px;border-radius:6px;border-left:3px solid}
.cv-alert{background:rgba(226,85,126,.1);border-color:var(--rose);color:#FFA9C0}
.cv-warn{background:rgba(240,151,28,.1);border-color:var(--amber);color:var(--amber-1)}
.cv-info{background:rgba(46,146,240,.1);border-color:var(--blue);color:var(--blue-1)}
.case-src{font-family:var(--fm);font-size:9.5px;color:#6B7280;margin-top:12px;letter-spacing:.02em}
.crisis-thesis{margin-top:clamp(36px,4vw,52px);padding:clamp(30px,4vw,46px);
  border:1px solid rgba(240,151,28,.3);border-radius:10px;background:rgba(240,151,28,.06);position:relative}
.crisis-thesis::before{content:'TESIS EDITORIAL';position:absolute;top:0;left:28px;transform:translateY(-50%);
  background:var(--amber);color:var(--ink);font-family:var(--fm);font-size:9px;font-weight:600;letter-spacing:.1em;padding:4px 11px;border-radius:3px}
.ct-text{font-family:var(--fd);font-weight:700;font-size:clamp(17px,2vw,26px);color:#fff;line-height:1.3;letter-spacing:-.015em;max-width:46ch}
.ct-text em{font-style:normal;color:var(--amber-1)}

/* ════════ IMAGE SHARD BANNER ════════ */
.sphoto{position:relative;height:clamp(180px,24vw,300px);overflow:hidden;background:var(--gray-100)}
.sphoto-grid{position:absolute;inset:0;display:flex}
.sphoto-grid .pane{flex:1;position:relative;overflow:hidden}
.sphoto-grid .pane img{width:100%;height:100%;object-fit:cover;filter:grayscale(.25)}
.sphoto-shard{position:absolute;top:0;bottom:0;width:46%;clip-path:var(--shard);z-index:2}
.sphoto-label{position:absolute;inset:0;display:flex;align-items:flex-end;padding:clamp(20px,4vw,40px);z-index:3}
.sphoto-text{font-family:var(--fm);font-size:11px;color:#fff;letter-spacing:.08em;text-transform:uppercase;
  background:rgba(21,22,27,.7);padding:8px 14px;border-radius:4px;backdrop-filter:blur(4px)}

/* ════════ SEVERITY ════════ */
.sev-grid{display:grid;grid-template-columns:1fr 1fr;gap:1px;background:var(--border);
  border:1px solid var(--border);border-radius:8px;overflow:hidden;margin-top:clamp(36px,4vw,52px)}
.sev-cell{background:var(--paper);padding:30px 30px}
.sev-label{font-family:var(--fm);font-size:10px;color:var(--lilac-deep);letter-spacing:.06em;text-transform:uppercase;
  margin-bottom:14px;padding-bottom:12px;border-bottom:1px solid var(--border);font-weight:500}
.sev-title{font-family:var(--fd);font-weight:700;font-size:18px;color:var(--ink);margin-bottom:12px;line-height:1.2;letter-spacing:-.01em}
.sev-body{font-size:13.5px;color:var(--text-2);line-height:1.6}
.sev-body strong{color:var(--ink);font-weight:600}
.hamd-compare{display:grid;grid-template-columns:repeat(3,1fr);gap:1px;background:var(--border);
  border:1px solid var(--border);border-radius:8px;overflow:hidden;margin-top:clamp(28px,3vw,40px)}
.hc-col{background:var(--paper);padding:24px 24px}
.hc-col.is-trial{background:var(--rose-0)}
.hc-col.is-key{background:var(--lilac-0)}
.hc-score{font-family:var(--fd);font-weight:800;font-size:38px;line-height:.9;margin-bottom:14px;letter-spacing:-.03em;color:var(--ink)}
.hc-col.is-trial .hc-score{color:var(--rose-deep)}
.hc-col.is-key .hc-score{color:var(--lilac-deep)}
.hc-bar{height:5px;border-radius:3px;margin-bottom:18px;background:var(--gray-200)}
.hc-label{font-family:var(--fd);font-weight:600;font-size:13px;color:var(--ink);margin-bottom:10px;line-height:1.3}
.hc-desc{font-size:12px;color:var(--text-2);line-height:1.55}
.hc-conclusion{margin-top:clamp(28px,3vw,40px);padding:clamp(26px,3vw,40px);background:var(--lilac-0);
  border:1px solid var(--lilac-1);border-radius:10px}
.hc-conclusion-text{font-family:var(--fd);font-weight:700;font-size:clamp(17px,2vw,26px);color:var(--ink);line-height:1.3;letter-spacing:-.015em;max-width:48ch}
.hc-conclusion-text em{font-style:normal;color:var(--lilac-deep)}

/* ════════ RESPONDERS ════════ */
.resp-intro{font-family:var(--fd);font-weight:700;font-size:clamp(20px,2.6vw,34px);color:var(--ink);
  line-height:1.18;max-width:26ch;margin:clamp(28px,3vw,40px) 0;letter-spacing:-.025em}
.resp-intro em{font-style:normal;color:var(--lilac)}
.resp-hero{display:grid;grid-template-columns:1.05fr .95fr;gap:1px;background:var(--border);
  border:1px solid var(--border);border-radius:10px;overflow:hidden;margin-top:clamp(28px,3vw,42px)}
.resp-hero-copy{background:var(--lilac-0);padding:clamp(28px,3vw,40px)}
.resp-hero-k{font-family:var(--fm);font-size:10px;color:var(--lilac-deep);letter-spacing:.08em;text-transform:uppercase;margin-bottom:14px;font-weight:500}
.resp-hero-title{font-family:var(--fd);font-weight:800;font-size:clamp(22px,2.6vw,34px);line-height:1.05;color:var(--ink);letter-spacing:-.025em;max-width:16ch}
.resp-hero-body{font-size:14px;color:var(--text-2);line-height:1.6;margin-top:18px}
.resp-hero-body strong{color:var(--ink);font-weight:600}
.resp-scoreboard{display:grid;grid-template-columns:repeat(2,1fr);gap:1px;background:var(--border)}
.rs-cell{background:var(--paper);padding:24px 24px;position:relative;min-height:160px}
.rs-cell::before{content:'';position:absolute;left:0;top:24px;bottom:24px;width:3px;background:var(--lilac)}
.rs-cell:nth-child(2)::before{background:var(--rose)}
.rs-cell:nth-child(3)::before{background:var(--blue)}
.rs-cell:nth-child(4)::before{background:var(--amber)}
.rs-n{font-family:var(--fd);font-weight:800;font-size:clamp(34px,4vw,50px);color:var(--ink);line-height:.85;letter-spacing:-.04em;margin-bottom:12px}
.rs-l{font-family:var(--fm);font-size:10px;letter-spacing:.06em;text-transform:uppercase;margin-bottom:10px;font-weight:500;color:var(--lilac-deep)}
.rs-cell:nth-child(2) .rs-l{color:var(--rose-deep)}
.rs-cell:nth-child(3) .rs-l{color:var(--blue-deep)}
.rs-cell:nth-child(4) .rs-l{color:var(--amber-deep)}
.rs-b{font-size:12px;color:var(--text-2);line-height:1.5}

.resp-grid{display:grid;grid-template-columns:repeat(4,1fr);gap:1px;background:var(--border);
  border:1px solid var(--border);border-radius:10px;overflow:hidden;margin-top:clamp(28px,3vw,40px)}
.resp-card{background:var(--paper);padding:26px 24px;transition:background .16s;position:relative}
.resp-card::after{content:'';position:absolute;left:24px;right:24px;bottom:0;height:3px;background:var(--lilac);opacity:.65}
.resp-card:hover{background:var(--gray-50)}
.resp-k{font-family:var(--fm);font-size:10px;color:var(--text-3);letter-spacing:.05em;text-transform:uppercase;margin-bottom:14px}
.resp-title{font-family:var(--fd);font-weight:700;font-size:17px;color:var(--ink);line-height:1.18;margin-bottom:12px;letter-spacing:-.015em}
.resp-body{font-size:12.8px;color:var(--text-2);line-height:1.6}
.resp-body strong{color:var(--ink);font-weight:600}
.resp-tag{display:inline-flex;margin-top:16px;font-family:var(--fm);font-size:9.5px;letter-spacing:.04em;text-transform:uppercase;
  border:1px solid var(--lilac-1);color:var(--lilac-deep);background:var(--lilac-0);border-radius:3px;padding:5px 9px}

.responder-matrix{display:grid;grid-template-columns:.9fr 1.1fr;gap:1px;background:var(--lilac-1);
  border:1px solid var(--lilac-1);border-radius:10px;overflow:hidden;margin-top:clamp(28px,3vw,42px)}
.rm-head{background:var(--lilac);color:#fff;padding:clamp(28px,3vw,42px)}
.rm-k{font-family:var(--fm);font-size:10px;color:#fff;opacity:.85;letter-spacing:.08em;text-transform:uppercase;margin-bottom:14px}
.rm-title{font-family:var(--fd);font-weight:800;font-size:clamp(20px,2.4vw,30px);line-height:1.08;color:#fff;max-width:18ch;letter-spacing:-.02em}
.rm-body{font-size:13.5px;color:rgba(255,255,255,.9);line-height:1.6;margin-top:16px}
.rm-grid{display:grid;grid-template-columns:repeat(2,1fr);gap:1px;background:var(--lilac-1)}
.rm-cell{background:var(--paper);padding:24px 26px}
.rm-n{font-family:var(--fm);font-size:10px;color:var(--lilac-deep);letter-spacing:.06em;text-transform:uppercase;margin-bottom:12px;font-weight:500}
.rm-h{font-family:var(--fd);font-weight:700;font-size:16px;color:var(--ink);line-height:1.2;margin-bottom:8px;letter-spacing:-.01em}
.rm-p{font-size:12.5px;color:var(--text-2);line-height:1.55}

.bioflow{display:grid;grid-template-columns:repeat(3,1fr);gap:1px;background:var(--border);
  border:1px solid var(--border);border-radius:10px;overflow:hidden;margin-top:clamp(28px,3vw,42px)}
.bf-cell{background:var(--paper);padding:28px 28px;position:relative}
.bf-cell::before{content:'';position:absolute;left:0;right:0;top:0;height:4px;background:var(--blue)}
.bf-cell:nth-child(2)::before{background:var(--amber)}
.bf-cell:nth-child(3)::before{background:var(--rose)}
.bf-n{font-family:var(--fm);font-size:10px;color:var(--blue-deep);letter-spacing:.06em;text-transform:uppercase;margin-bottom:14px;font-weight:500}
.bf-cell:nth-child(2) .bf-n{color:var(--amber-deep)}
.bf-cell:nth-child(3) .bf-n{color:var(--rose-deep)}
.bf-h{font-family:var(--fd);font-weight:700;font-size:18px;color:var(--ink);line-height:1.18;margin-bottom:12px;letter-spacing:-.015em}
.bf-copy{font-size:13px;color:var(--text-2);line-height:1.6}
.bf-copy strong{color:var(--ink);font-weight:600}
.bf-pill{display:inline-flex;margin-top:18px;font-family:var(--fm);font-size:9.5px;letter-spacing:.04em;text-transform:uppercase;
  border:1px solid var(--border-2);border-radius:999px;padding:6px 11px;color:var(--text-2)}
.resp-thesis{margin-top:clamp(34px,4vw,50px);padding:clamp(30px,4vw,48px);border-radius:12px;position:relative;overflow:visible;
  background:linear-gradient(120deg,var(--lilac-0),var(--blue-0));border:1px solid var(--lilac-1)}
.resp-thesis::before{content:'HIPÓTESIS PLUSEVO';position:absolute;top:0;left:28px;transform:translateY(-50%);
  background:var(--lilac);color:#fff;font-family:var(--fm);font-size:9px;font-weight:600;letter-spacing:.1em;padding:4px 11px;border-radius:3px}
.resp-thesis-text{font-family:var(--fd);font-weight:700;font-size:clamp(18px,2.1vw,28px);color:var(--ink);line-height:1.28;letter-spacing:-.02em;max-width:52ch;position:relative;z-index:1}
.resp-thesis-text em{font-style:normal;color:var(--lilac-deep)}

.charts-wrap{margin:clamp(34px,4vw,52px) 0}
.charts-head{display:grid;grid-template-columns:.8fr 1.2fr;gap:clamp(20px,3vw,40px);align-items:end;margin-bottom:24px}
.charts-k{font-family:var(--fm);font-size:10px;color:var(--lilac-deep);letter-spacing:.08em;text-transform:uppercase;margin-bottom:10px;font-weight:500}
.charts-title{font-family:var(--fd);font-weight:800;font-size:clamp(22px,2.6vw,34px);line-height:1.05;color:var(--ink);letter-spacing:-.025em;max-width:18ch}
.charts-sub{font-size:14px;color:var(--text-2);line-height:1.6}
.charts-sub strong{color:var(--ink);font-weight:600}
.charts-grid{display:grid;grid-template-columns:repeat(3,1fr);gap:1px;background:var(--border);border:1px solid var(--border);border-radius:10px;overflow:hidden}
.chart-card{background:var(--paper);padding:24px 22px}
.chart-mini{height:200px;display:flex;align-items:center;justify-content:center;background:var(--gray-50);border-radius:8px;padding:18px;margin-bottom:18px}
.chart-title{font-family:var(--fd);font-weight:700;font-size:15.5px;color:var(--ink);line-height:1.25;margin-bottom:10px;letter-spacing:-.01em}
.chart-copy{font-size:12.5px;color:var(--text-2);line-height:1.6}
.chart-copy strong{color:var(--ink);font-weight:600}
.chart-note{margin-top:14px;font-family:var(--fm);font-size:9.5px;color:var(--text-3);line-height:1.5;border-top:1px solid var(--border);padding-top:12px}

/* ════════ DRUG MODULE ════════ */
.warn-box{display:block;margin:14px 0 clamp(32px,4vw,44px);padding:16px 18px;border:1px solid var(--amber-1);
  border-radius:8px;background:var(--amber-0);font-size:13.5px;color:#6B4A12;line-height:1.55;max-width:none}
.warn-box .wk{display:block;font-family:var(--fm);font-size:9.5px;letter-spacing:.1em;text-transform:uppercase;color:var(--amber-deep);margin-bottom:8px;font-weight:500}
.drug-tabs{display:flex;gap:7px;flex-wrap:wrap;margin-bottom:clamp(24px,3vw,34px)}
.dtab{font-family:var(--fm);font-size:11px;padding:8px 15px;border-radius:999px;border:1px solid var(--border-2);
  background:var(--paper);color:var(--text-2);cursor:pointer;transition:all .15s;letter-spacing:.02em;font-weight:500}
.dtab:hover{border-color:var(--ink);color:var(--ink)}
.dtab.on{background:var(--ink);border-color:var(--ink);color:#fff}
.drug-grid{display:grid;grid-template-columns:repeat(auto-fill,minmax(310px,1fr));gap:1px;background:var(--border);
  border:1px solid var(--border);border-radius:10px;overflow:hidden}
.dcard{background:var(--paper);padding:24px 24px;transition:background .15s}
.dcard:hover{background:var(--gray-50)}
.dcard-cat{font-family:var(--fm);font-size:10px;letter-spacing:.06em;text-transform:uppercase;margin-bottom:10px;font-weight:500}
.dcard-name{font-family:var(--fd);font-weight:800;font-size:24px;color:var(--ink);line-height:1.05;margin-bottom:3px;letter-spacing:-.02em}
.dcard-generic{font-family:var(--fm);font-size:10.5px;color:var(--text-3);margin-bottom:14px;letter-spacing:.01em}
.dcard-context{font-size:12.5px;color:var(--text-2);line-height:1.55;margin-bottom:16px}
.dcard-context strong{color:var(--ink);font-weight:600}
.bars{display:flex;flex-direction:column;gap:10px;margin-bottom:14px}
.bar-row{display:flex;flex-direction:column;gap:4px}
.bar-meta{display:flex;justify-content:space-between;align-items:baseline}
.bar-nm{font-family:var(--fm);font-size:10.5px;color:var(--text-2)}
.bar-vl{font-family:var(--fm);font-size:12px;font-weight:500}
.bar-track{height:8px;background:var(--gray-100);border-radius:4px;overflow:hidden}
.bar-fill{height:100%;border-radius:4px}
.bf-d{background:var(--ink)}
.bf-p{background:var(--lilac)}
.bf-o{background:var(--blue)}
.unit-note{font-family:var(--fm);font-size:9.5px;color:var(--text-3);margin-bottom:12px;letter-spacing:.01em}
.verdict{padding:11px 13px;border-radius:6px;font-size:11.5px;line-height:1.45;border-left:3px solid}
.v-warn{background:var(--amber-0);border-color:var(--amber);color:#6B4A12}
.v-info{background:var(--blue-0);border-color:var(--blue);color:#13548F}
.v-ok{background:var(--lilac-0);border-color:var(--lilac);color:var(--lilac-deep)}
.v-alert{background:var(--rose-0);border-color:var(--rose);color:var(--rose-deep)}
.v-purple{background:var(--lilac-0);border-color:var(--lilac);color:var(--lilac-deep)}
.dcard-src{font-family:var(--fm);font-size:9.5px;color:var(--text-3);padding-top:12px;border-top:1px solid var(--border);margin-top:12px;letter-spacing:.01em}

.insight-row{display:grid;grid-template-columns:repeat(3,1fr);gap:1px;margin-top:clamp(28px,3vw,40px);
  background:var(--ink);border:1px solid var(--ink);border-radius:10px;overflow:hidden}
.ir-cell{background:var(--ink);padding:28px 26px}
.ir-cell+.ir-cell{box-shadow:-1px 0 0 rgba(255,255,255,.1)}
.ir-n{font-family:var(--fd);font-weight:800;font-size:46px;line-height:.9;margin-bottom:10px;letter-spacing:-.04em;color:#fff}
.ir-n.ca{color:var(--lilac-2)}.ir-n.cb{color:var(--amber-1)}.ir-n.cc{color:var(--blue-1)}
.ir-l{font-size:12px;color:#AfB3BE;line-height:1.5;font-family:var(--fm)}

/* ════════ MECHANISMS · ACCORDION (signature) ════════ */
.mech-acc{display:flex;flex-direction:column;gap:0;margin-top:clamp(36px,4vw,52px);border-radius:10px;overflow:hidden}
.macc{border:none;cursor:pointer;position:relative;overflow:hidden;transition:flex .3s ease}
.macc-head{display:grid;grid-template-columns:auto auto 1fr auto;align-items:center;gap:18px;padding:22px clamp(20px,3vw,32px)}
.macc-num{font-family:var(--fm);font-size:13px;font-weight:500;color:rgba(21,22,27,.65)}
.macc-arrow{font-family:var(--fd);font-weight:700;font-size:15px;color:rgba(21,22,27,.65)}
.macc-title{font-family:var(--fd);font-weight:700;font-size:clamp(16px,1.9vw,22px);letter-spacing:-.01em;color:var(--ink);line-height:1.1}
.macc-plus{width:34px;height:34px;border-radius:50%;border:1.5px solid rgba(21,22,27,.4);display:flex;align-items:center;justify-content:center;
  font-family:var(--fd);font-weight:500;font-size:20px;color:var(--ink);transition:transform .3s}
.macc-body{max-height:0;overflow:hidden;transition:max-height .35s ease;padding:0 clamp(20px,3vw,32px)}
.macc-body-in{padding:0 0 26px;display:grid;grid-template-columns:1fr 1fr;gap:24px;max-width:none}
.macc-sub{font-family:var(--fd);font-weight:600;font-size:16px;color:var(--ink);margin-bottom:10px}
.macc-text{font-size:13.5px;color:rgba(21,22,27,.78);line-height:1.6}
.macc-text strong{color:var(--ink);font-weight:600}
.macc.on .macc-plus{transform:rotate(45deg)}
.macc.on .macc-body{max-height:600px}
.macc.amber{background:var(--amber-1)} .macc.amber.on{background:var(--amber-1)}
.macc.blue{background:var(--blue-1)}
.macc.lilac{background:var(--lilac-2)}
.macc.magenta{background:var(--magenta-1)}
.macc-refs{margin-top:14px;display:flex;gap:6px;flex-wrap:wrap}

/* ════════ TIMELINE ════════ */
.tl-filters{display:flex;gap:7px;flex-wrap:wrap;margin-bottom:clamp(34px,4vw,48px)}
.tfbtn{font-family:var(--fm);font-size:11px;padding:8px 15px;border-radius:999px;border:1px solid var(--border-2);
  background:var(--paper);color:var(--text-2);cursor:pointer;transition:all .15s;letter-spacing:.02em;font-weight:500}
.tfbtn:hover{border-color:var(--ink);color:var(--ink)}
.tfbtn.on{background:var(--ink);border-color:var(--ink);color:#fff}
.tl{position:relative}
.tl-spine{position:absolute;left:96px;top:0;bottom:0;width:2px;background:var(--border)}
.tl-era{padding:30px 0 10px 124px;font-family:var(--fm);font-size:10px;color:var(--text-3);letter-spacing:.08em;text-transform:uppercase;position:relative;font-weight:500}
.tl-era::before{content:'';position:absolute;left:84px;top:40px;width:24px;height:2px;background:var(--border-2)}
.tl-item{display:flex;position:relative;cursor:pointer}
.tl-item:hover .tlc{background:var(--gray-50)}
.tlyr{width:96px;flex:none;padding:16px 18px 16px 0;text-align:right}
.tlyrn{font-family:var(--fm);font-size:11px;color:var(--text-3);letter-spacing:.02em}
.tld{width:0;flex:none;position:relative}
.dot{position:absolute;left:-5px;top:21px;width:9px;height:9px;border-radius:50%;background:var(--paper);border:2px solid var(--text-3);z-index:2;transition:all .15s}
.dot.m{border-color:var(--blue);width:11px;height:11px;left:-6px;top:20px}
.dot.k{border-color:var(--amber);width:13px;height:13px;left:-7px;top:19px}
.dot.o{border-color:var(--blue);background:var(--blue-0);width:13px;height:13px;left:-7px;top:19px}
.dot.p{border-color:var(--lilac);background:var(--lilac);width:15px;height:15px;left:-8px;top:18px}
.tl-item:hover .dot,.tl-item.open .dot{background:var(--text-3)}
.tl-item:hover .dot.k,.tl-item.open .dot.k{background:var(--amber)}
.tl-item:hover .dot.m,.tl-item.open .dot.m{background:var(--blue)}
.tlc{padding:14px 0 14px 24px;flex:1;border-radius:6px;transition:background .12s}
.tlh{font-family:var(--fd);font-weight:600;font-size:14.5px;color:var(--ink);line-height:1.3;letter-spacing:-.005em}
.tls{font-family:var(--fm);font-size:11px;color:var(--text-2);margin-top:4px}
.tltags{display:flex;gap:5px;flex-wrap:wrap;margin-top:9px}
.tag{font-family:var(--fm);font-size:9px;font-weight:500;padding:3px 8px;border-radius:3px;letter-spacing:.03em;border:1px solid}
.tag-root{background:var(--gray-100);color:var(--text-2);border-color:var(--border-2)}
.tag-method{background:var(--amber-0);color:var(--amber-deep);border-color:var(--amber-1)}
.tag-study{background:var(--blue-0);color:var(--blue-deep);border-color:var(--blue-1)}
.tag-neuro{background:var(--rose-0);color:var(--rose-deep);border-color:#F3B6C9}
.tag-olp{background:var(--blue-0);color:var(--blue-deep);border-color:var(--blue-1)}
.tag-pharma{background:var(--amber-0);color:var(--amber-deep);border-color:var(--amber-1)}
.tag-plusevo{background:var(--lilac-0);color:var(--lilac-deep);border-color:var(--lilac-1)}
.tl-detail{display:none;font-size:13px;color:var(--text-2);margin-top:12px;line-height:1.65;
  padding:16px 18px;background:var(--gray-50);border:1px solid var(--border);border-radius:8px}
.tl-item.open .tl-detail{display:block}
.tl-detail strong{color:var(--ink);font-weight:600}

/* ════════ STUDIES ════════ */
.studies-grid{display:grid;grid-template-columns:repeat(auto-fill,minmax(300px,1fr));gap:1px;background:var(--border);
  border:1px solid var(--border);border-radius:10px;overflow:hidden;margin-top:clamp(34px,4vw,48px)}
.scard{background:var(--paper);padding:24px 24px;display:flex;flex-direction:column;transition:background .15s}
.scard:hover{background:var(--gray-50)}
.sj{font-family:var(--fm);font-size:9.5px;color:var(--lilac-deep);letter-spacing:.04em;text-transform:uppercase;
  margin-bottom:12px;padding-bottom:12px;border-bottom:1px solid var(--border);font-weight:500}
.st2{font-family:var(--fd);font-weight:700;font-size:15px;color:var(--ink);line-height:1.25;margin-bottom:10px;flex:1;letter-spacing:-.01em}
.sbody{font-size:12.5px;color:var(--text-2);line-height:1.55;margin-bottom:16px}
.sstat{font-family:var(--fd);font-weight:800;font-size:34px;margin-bottom:4px;letter-spacing:-.03em;color:var(--ink)}
.sstat.ca{color:var(--lilac-deep)}.sstat.cb{color:var(--amber-deep)}.sstat.cc{color:var(--blue-deep)}.sstat.ce{color:var(--magenta)}
.sstat-l{font-family:var(--fm);font-size:10.5px;color:var(--text-2)}
.sau{font-family:var(--fm);font-size:9.5px;color:var(--text-3);margin-top:auto;padding-top:14px;border-top:1px solid var(--border)}

/* ════════ OLP LAYERS ════════ */
.olp-pull{font-family:var(--fd);font-weight:700;font-size:clamp(18px,2.1vw,28px);color:var(--ink);line-height:1.3;
  border-left:4px solid var(--lilac);padding-left:26px;margin:clamp(34px,4vw,48px) 0;max-width:42ch;letter-spacing:-.015em}
.olp-pull em{font-style:normal;color:var(--lilac-deep)}
.layers-grid{display:grid;grid-template-columns:repeat(3,1fr);gap:1px;background:var(--border);
  border:1px solid var(--border);border-radius:10px;overflow:hidden;margin-top:clamp(28px,3vw,42px)}
.layer-cell{background:var(--paper);padding:28px 26px;min-height:280px;position:relative}
.layer-num{font-family:var(--fm);font-size:10px;color:var(--lilac-deep);letter-spacing:.06em;text-transform:uppercase;margin-bottom:16px;font-weight:500}
.layer-title{font-family:var(--fd);font-weight:700;font-size:19px;color:var(--ink);margin-bottom:14px;line-height:1.15;letter-spacing:-.015em}
.layer-body{font-size:13.5px;color:var(--text-2);line-height:1.65}
.layer-note{margin-top:18px;padding-top:14px;border-top:1px solid var(--border);font-family:var(--fm);font-size:10px;color:var(--text-3);letter-spacing:.01em}
.layer-featured{grid-column:1/-1;min-height:auto;padding:0;background:linear-gradient(120deg,var(--lilac-0),var(--blue-0))}
.layer-featured-in{display:grid;grid-template-columns:1.2fr .8fr;gap:clamp(24px,3vw,40px);padding:clamp(30px,3.5vw,44px)}
.layer-featured .layer-num{color:var(--lilac-deep)}
.layer-featured .layer-title{font-size:clamp(24px,2.8vw,34px);line-height:1.0;margin-bottom:16px;letter-spacing:-.025em}
.layer-featured .layer-body{font-size:15px;max-width:60ch}
.layer-proof{display:flex;flex-wrap:wrap;gap:8px;margin-top:20px}
.layer-pill{display:inline-flex;align-items:center;padding:7px 13px;border-radius:999px;border:1px solid var(--lilac-1);background:rgba(255,255,255,.6);font-family:var(--fm);font-size:10.5px;color:var(--lilac-deep)}
.layer-mini{font-family:var(--fm);font-size:10.5px;color:var(--text-2);margin-top:16px;line-height:1.5}
.layer-chip-grid{display:grid;grid-template-columns:repeat(2,1fr);gap:10px;align-content:start}
.layer-chip{background:var(--paper);border:1px solid var(--border);border-radius:10px;padding:14px 14px}
.layer-chip-k{font-family:var(--fm);font-size:9px;color:var(--lilac-deep);letter-spacing:.06em;text-transform:uppercase;margin-bottom:6px;font-weight:500}
.layer-chip-v{font-family:var(--fd);font-weight:600;font-size:13px;color:var(--ink);line-height:1.25}

/* ════════ BRIDGE / CTA ════════ */
.bridge-in{border-radius:14px;padding:clamp(40px,5vw,72px);position:relative;overflow:hidden;
  background:var(--ink);color:#EDEEF2}
.bridge-in .shardstack span:nth-child(1){left:62%;background:rgba(124,122,247,.22)}
.bridge-in .shardstack span:nth-child(2){left:80%;background:rgba(46,146,240,.16)}
.bridge-in .ey{color:var(--lilac-2)}
.bridge-in .ey::before{color:var(--lilac-2)}
.btitle{font-family:var(--fd);font-weight:800;font-size:clamp(26px,4vw,52px);color:#fff;line-height:.98;margin-bottom:20px;letter-spacing:-.03em;max-width:18ch;position:relative;z-index:2}
.bbody{font-size:15px;color:#AfB3BE;line-height:1.6;max-width:60ch;margin-bottom:clamp(28px,3vw,40px);position:relative;z-index:2}
.bbody strong{color:#fff;font-weight:600}
.bproducts{display:grid;grid-template-columns:repeat(3,1fr);gap:1px;background:rgba(255,255,255,.1);border:1px solid rgba(255,255,255,.1);border-radius:8px;overflow:hidden;margin-bottom:clamp(28px,3vw,38px);position:relative;z-index:2}
.bp{background:var(--ink-2);padding:18px 18px}
.bpn{font-family:var(--fd);font-weight:700;font-size:14px;color:#fff;margin-bottom:3px;letter-spacing:-.01em}
.bpc{font-size:12px;color:#9CA2AE;margin-bottom:7px}
.bpp{font-family:var(--fm);font-size:9.5px;color:var(--lilac-2);letter-spacing:.02em}
.bcta{display:flex;gap:12px;flex-wrap:wrap;position:relative;z-index:2}
.btn-p{display:inline-flex;align-items:center;gap:8px;background:var(--lilac);color:#fff;font-family:var(--fd);font-weight:600;font-size:14px;padding:14px 26px;border-radius:5px;text-decoration:none;transition:background .18s}
.btn-p:hover{background:var(--lilac-deep)}
.btn-s{display:inline-flex;align-items:center;gap:8px;background:transparent;color:#EDEEF2;font-family:var(--fd);font-weight:600;font-size:14px;padding:14px 26px;border-radius:5px;border:1px solid rgba(255,255,255,.25);text-decoration:none;transition:all .18s}
.btn-s:hover{border-color:#fff;background:rgba(255,255,255,.06)}

/* ════════ FOOTER ════════ */
footer{padding:clamp(40px,5vw,64px) 0;border-top:1px solid var(--border);background:var(--gray-50)}
.fi{display:flex;justify-content:space-between;align-items:flex-start;flex-wrap:wrap;gap:24px}
.fbrand{display:flex;align-items:center;gap:11px;margin-bottom:14px;color:var(--ink);text-decoration:none}
.fb{font-family:var(--fm);font-size:12px;color:var(--text-2)}
.fd2{font-family:var(--fm);font-size:11px;color:var(--text-3);max-width:54ch;line-height:1.65}

/* ════════ REFERENCES ════════ */
.ref-inline{display:inline-flex;align-items:center;gap:3px;position:relative;vertical-align:baseline;margin:0 1px}
.ref-btn{display:inline-flex;align-items:center;justify-content:center;font-family:var(--fm);font-size:9.5px;font-weight:500;
  min-width:18px;height:18px;padding:0 6px;border-radius:3px;border:1px solid var(--lilac-1);background:var(--lilac-0);
  color:var(--lilac-deep);cursor:pointer;text-decoration:none;letter-spacing:.02em;transition:all .15s;white-space:nowrap;line-height:1}
.ref-btn:hover{background:var(--lilac);border-color:var(--lilac);color:#fff}
.bg-ink .ref-btn{background:rgba(124,122,247,.18);border-color:rgba(124,122,247,.4);color:var(--lilac-2)}
.ref-preview-portal{position:fixed;width:310px;background:var(--paper);border:1px solid var(--border-2);border-radius:10px;
  padding:16px 18px;box-shadow:0 24px 54px rgba(21,22,27,.16);z-index:9999;pointer-events:none;opacity:0;transition:opacity .15s;box-sizing:border-box}
.ref-preview-portal.visible{opacity:1;pointer-events:auto}
.ref-portal-close{display:none;position:absolute;top:10px;right:10px;background:none;border:none;
  font-size:1rem;color:var(--text-3);cursor:pointer;line-height:1;padding:4px}
@media(hover:none){.ref-portal-close{display:block}}
.rp-journal{font-family:var(--fm);font-size:9.5px;color:var(--lilac-deep);letter-spacing:.06em;text-transform:uppercase;margin-bottom:8px;font-weight:500}
.rp-title{font-family:var(--fd);font-weight:700;font-size:13px;color:var(--ink);line-height:1.35;margin-bottom:8px}
.rp-authors{font-size:11.5px;color:var(--text-2);margin-bottom:4px;line-height:1.4}
.rp-year{font-family:var(--fm);font-size:10px;color:var(--text-3);margin-bottom:12px}
.rp-abstract{font-size:11.5px;color:var(--text-2);line-height:1.55;border-top:1px solid var(--border);padding-top:10px}
.rp-link{display:inline-flex;align-items:center;gap:5px;margin-top:10px;font-family:var(--fm);font-size:10.5px;color:var(--lilac-deep);
  text-decoration:none;border-top:1px solid var(--border);padding-top:10px;width:100%}
.ref-strip{display:flex;flex-wrap:wrap;gap:5px;margin-top:12px;padding-top:10px;border-top:1px solid var(--border)}
.bg-ink .ref-strip{border-color:rgba(255,255,255,.12)}

/* ════════ HAMBURGER & MOBILE DRAWER ════════ */
.ham{display:none;flex-direction:column;justify-content:center;align-items:center;
  gap:5px;width:38px;height:38px;background:none;border:none;cursor:pointer;padding:6px;
  -webkit-tap-highlight-color:transparent;flex-shrink:0}
.ham span{display:block;width:20px;height:2px;background:var(--ink);border-radius:2px;
  transition:transform .28s ease,opacity .2s ease}
.ham.open span:nth-child(1){transform:translateY(7px) rotate(45deg)}
.ham.open span:nth-child(2){opacity:0;transform:scaleX(0)}
.ham.open span:nth-child(3){transform:translateY(-7px) rotate(-45deg)}

.mob-overlay{display:none;position:fixed;inset:0;background:rgba(0,0,0,.45);
  z-index:298;backdrop-filter:blur(2px)}
.mob-overlay.show{display:block}

.mob-drawer{position:fixed;top:0;right:0;bottom:0;width:min(280px,82vw);
  background:#fff;z-index:299;
  transform:translateX(100%);transition:transform .32s cubic-bezier(.4,0,.2,1);
  display:flex;flex-direction:column;box-shadow:-4px 0 32px rgba(0,0,0,.12)}
.mob-drawer.open{transform:translateX(0)}

.mob-drawer-head{display:flex;align-items:center;justify-content:space-between;
  padding:16px 20px;border-bottom:1px solid var(--border)}
.mob-close{background:none;border:none;cursor:pointer;font-size:1.2rem;
  color:var(--text-3);width:32px;height:32px;display:flex;align-items:center;
  justify-content:center;border-radius:6px}
.mob-close:hover{background:var(--gray-50)}

.mob-links{display:flex;flex-direction:column;flex:1;min-height:0;overflow-y:auto;padding:8px 0}
.mob-links a{font-family:var(--fm);font-size:13px;font-weight:500;
  color:var(--text-2);padding:13px 20px;text-decoration:none;
  border-bottom:1px solid var(--border);transition:background .15s,color .15s}
.mob-links a:hover{background:var(--gray-50);color:var(--ink)}

.mob-cta-link{background:var(--ink)!important;color:#fff!important;font-weight:700!important;
  text-align:center;justify-content:center;margin:12px 16px;border-radius:6px;
  border-bottom:none!important;width:calc(100% - 32px)!important;box-sizing:border-box}

/* ════════ RED CIENTÍFICA — CONTACTO ════════ */
.science-contact{background:var(--ink);color:#EDEEF2}
.sc-inner{max-width:680px;margin:0 auto;text-align:center}
.sc-eye{font-family:var(--fm);font-size:10px;letter-spacing:.14em;text-transform:uppercase;
  color:var(--lilac-2);margin-bottom:1.2rem}
.sc-h{font-family:var(--fd);font-weight:800;font-size:clamp(1.7rem,3.5vw,2.6rem);
  letter-spacing:-.03em;line-height:1.15;margin-bottom:.9rem}
.sc-h em{font-style:italic;color:rgba(255,255,255,.45)}
.sc-sub{font-size:.9rem;color:rgba(255,255,255,.5);line-height:1.7;margin-bottom:2.5rem}
.sc-form{display:flex;flex-direction:column;gap:14px;text-align:left}
.sc-row{display:grid;grid-template-columns:1fr 1fr;gap:14px}
.sc-fg{display:flex;flex-direction:column;gap:5px}
.sc-fg label{font-family:var(--fm);font-size:10.5px;letter-spacing:.06em;text-transform:uppercase;
  color:rgba(255,255,255,.4)}
.sc-fg input,.sc-fg textarea,.sc-fg select{
  background:rgba(255,255,255,.06);border:1.5px solid rgba(255,255,255,.12);
  border-radius:6px;padding:11px 14px;
  font-family:var(--fb);font-size:.88rem;color:#fff;
  transition:border-color .2s;outline:none;width:100%}
.sc-fg input::placeholder,.sc-fg textarea::placeholder{color:rgba(255,255,255,.25)}
.sc-fg input:focus,.sc-fg textarea:focus{border-color:var(--lilac)}
.sc-fg textarea{resize:vertical;min-height:100px}
.sc-submit{display:inline-flex;align-items:center;justify-content:center;gap:8px;
  background:var(--lilac);color:#fff;border:none;cursor:pointer;
  font-family:var(--fd);font-weight:700;font-size:.9rem;
  padding:14px 32px;border-radius:6px;width:100%;margin-top:6px;
  transition:background .2s}
.sc-submit:hover{background:var(--lilac-deep)}
.sc-submit:disabled{opacity:.5;cursor:not-allowed}
.sc-success{display:none;text-align:center;padding:2.5rem 1rem}
.sc-success-icon{font-size:2.5rem;margin-bottom:.8rem}
.sc-success h3{font-family:var(--fd);font-weight:700;font-size:1.3rem;margin-bottom:.5rem}
.sc-success p{font-size:.88rem;color:rgba(255,255,255,.5)}

/* ════════ RESPONSIVE ════════ */
@media(min-width:901px){
  .mob-drawer,.mob-overlay{display:none!important}
  .ham{display:none!important}
}
@media(max-width:1080px){
  .case-grid{grid-template-columns:repeat(2,1fr)}
  .resp-grid{grid-template-columns:repeat(2,1fr)}
  .hbars{grid-template-columns:repeat(3,1fr)}
}
@media(max-width:900px){
  .nlinks{display:none}
  .ncta{display:none}
  .mob-cta{display:flex;align-items:center;justify-content:center;gap:7px;
    font-family:var(--fd);font-weight:600;font-size:13px;
    padding:12px 18px;background:var(--ink);color:#fff;
    text-decoration:none;border-radius:4px;width:100%;
    box-sizing:border-box;transition:background .18s}
  .mob-cta:hover{background:var(--lilac-deep)}
  .ham{display:flex}
  .chart-panel.on{grid-template-columns:1fr}
  .sum-grid,.resp-hero,.responder-matrix,.charts-head,.layer-featured-in{grid-template-columns:1fr}
  .sev-grid,.bioflow,.charts-grid,.layers-grid{grid-template-columns:1fr}
  .hamd-compare{grid-template-columns:1fr}
  .macc-body-in{grid-template-columns:1fr}
  .resp-scoreboard,.rm-grid{grid-template-columns:1fr 1fr}
  .bproducts{grid-template-columns:1fr 1fr}
}
@media(max-width:640px){
  .hbars{grid-template-columns:repeat(2,1fr)}
  .case-grid,.resp-grid,.insight-row,.resp-scoreboard,.rm-grid,.bproducts{grid-template-columns:1fr}
  .tl-spine{left:64px}.tlyr{width:64px}.tl-era{padding-left:90px}.tl-era::before{left:54px}
  .macc-head{grid-template-columns:auto 1fr auto;gap:12px}.macc-arrow{display:none}
  .donut{width:80%}

  /* Credibility strip — logos responsive */
  .cred-in{flex-direction:column !important;align-items:center !important;gap:10px !important;padding:20px 0 !important;text-align:center}
  .cred-logos{display:flex !important;flex-wrap:wrap !important;row-gap:8px !important;column-gap:20px !important;align-items:center !important;justify-content:center !important}
  .cred-logos span{font-size:12px !important;white-space:nowrap}

  /* Formulario red científica */
  .sc-row{grid-template-columns:1fr}
}